Description
The ViPrimePLUS Human T-lymphotropic Virus 2 RT-qPCR Kit is a Taqman probe-based real-time PCR assay for the detection of Human T-lymphotropic Virus 2 genome in clinical samples (e.g. serum blood).
Human T-Lymphotropic virus (HTLV) is a RNA retrovirus that predominantly affects the T lymphocytes in human. The Human Immunodeficiency virus (HIV) was once categorized in the HTLV genus before the reclassification in 1983. After 30 years from the initial discovery, 4 types of HTLV have been identified and among them, the most significant two are the HTLV 1 and 2, which have affected about 15-20million people worldwide. HTLV-1 is divided into 6 subclasses which are endemic to different regions. It causes multiple disorders such as the often fatal leukaemia, debilitative myelopathy, uveitis and dermatitis. However, HTLV-2, which consists of 4 subtypes, is associated with milder neurological disorder and chronic pulmonary infections. The novel HTLV-3 and HTLV-4 have been isolated in a few cases but they have little clinical significance. Mode of transmission is via breast milk, sexual contact and intravenous drug abuse.
ViPrimePLUS Human T-lymphotropic Virus 2 RT-qPCR Kit is intended for research use only.
Kit Component
- HTLV2 Primers and Probe Mix (HTLV2 PPM)
- Positive Control
- Internal Extraction Control Primers and Probe Mix (IEC PPM)
- Internal Extraction Control (IEC DNA)
- Nuclease Free Water
- Template Preparation Buffer
Product Specification
| Technology | Taqman probe-based real-time PCR assay |
| Type of Nucleic Acid Kit | RNA |
| Kit Storage | Shipped in room temperature, store at -20℃ on arrival |
| Sample Material | Clinical samples (e.g. serum blood) |
| Gene Target | Polymerase gene (Pol) |
| Detection Limit | 10 to <100 copies per reaction |
| Sensitivity & Specificity | Ct value 28±3 with probability of 95% |
| Controls Included | • Internal Extraction Control (IEC) as inhibition control • Positive control |
| Channels | • FAM channels detect pathogen amplicons • VIC/HEX channel detects IEC amplicons |
Ordering Information
| Catalog No | Description | Pack Size |
| QM5058 | ViPrimePLUS Human T-lymphotropic Virus 2 RT-qPCR Kit | 150 reactions |
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